How I treat thrombocytopenia in pregnancy.
نویسندگان
چکیده
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer monitoring and possible therapy. Two clinical scenarios are particularly relevant for their prevalence and the issues relating to their management. The first is the presence of isolated thrombocytopenia and the differential diagnosis between primary immune thrombocytopenia and gestational thrombocytopenia. The second is thrombocytopenia associated with preeclampsia and its look-alikes and their distinction from thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome. In this review, we describe a systematic approach to the diagnosis and treatment of these disease entities using a case presentation format. Our discussion includes the antenatal and perinatal management of both the mother and fetus.
منابع مشابه
How I Treat How I treat thrombocytopenia in pregnancy
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer monitoring and possible therapy. Two clinical scenarios are particularly relevant for their prevalence and the issues r...
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Background and purpose: After anemia thrombocytopenia is the most common disorder in pregnancy which is encountered in 10% of pregnancies. Thrombocytopenia in pregnant women may lead to maternal and neonatal morbidity. This condition could involve some complications in pregnancy, so diagnosing its causes is important for treatment. This study was performed to determine the incidence, causes and...
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Methods Five FMF patients, treated with anakinra during pregnancy were monitored for side effects, fetal and maternal outcomes. Results We present five FMF cases treated with Anakinra during pregnancy due to severe protracted febrile myalgia in 3, thrombocytopenia in 1 and amyloidosis in 1. One of these cases is among the 5 patients that have been previously reported (1). Throughout pregnancy n...
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Heparin-induced thrombocytopenia is a prothrombotic adverse drug effect induced by platelet-activating antibodies against multimolecular complexes of platelet factor 4 and heparin. Diagnosis rests on a clinical assessment of disease probability and laboratory testing. Management involves immediate discontinuation of heparin and initiation of an alternative anticoagulant. Because of the frequenc...
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عنوان ژورنال:
- Blood
دوره 121 1 شماره
صفحات -
تاریخ انتشار 2013